首页> 外国专利> IRON (III) -PYRAZINE-COMPLEX COMPOUNDS FOR TREATMENT AND PREVENTION OF PHENOMENA DEFICIENCY PHENOMENA IN THE BODY AND IRON-DEFICIENCY ANEMIA

IRON (III) -PYRAZINE-COMPLEX COMPOUNDS FOR TREATMENT AND PREVENTION OF PHENOMENA DEFICIENCY PHENOMENA IN THE BODY AND IRON-DEFICIENCY ANEMIA

机译:铁(III)-吡嗪复合物用于治疗和预防机体缺铁现象和缺铁性贫血的现象

摘要

1. The complex compound iron (III) -pyrazin-2-ol-1-oxide or its pharmaceutically acceptable salts for use in the treatment and prevention of the phenomena of iron deficiency and iron deficiency anemia, as well as their accompanying symptoms. A complex compound of iron (III) for use according to claim 1, containing at least one ligand of the formula (I): where the arrows indicate the coordination bond with one or different iron atoms, R, R, R can be the same or different and are selected from a group consisting of: hydrogen, halogen, optionally substituted alkyl, optionally substituted alkoxyl, optionally substituted aryl, optionally substituted alkoxycarbonyl and optionally substituted aminocarbonyl, or R, R together with the carbon atoms to which they are bonded if necessary, form a substituted 5- or 6-membered saturated or unsaturated ring, which may optionally contain one or more heteroatoms, or pharmaceutically acceptable salts thereof. 3. A complex compound of iron (III) for use according to claim 2, containing at least one ligand of the formula (I): where the arrows indicate the coordination bond with one or different iron atoms, R, R, R can be the same or different, and selected from the group consisting of: hydrogen, optionally substituted alkyl, halogen, or R, R, together with the carbon atoms to which they are attached, form a 5- or 6-membered carbocyclic ring, or pharmaceutically acceptable salts thereof. 4. A complex compound of iron (III) for use according to claim 3, containing at least one ligand of the formula (I): where the arrows indicate the coordination bond with one or different iron atoms, R, R, R can be the same or different and select
机译:1.用于治疗和预防铁缺乏症和铁缺乏性贫血现象及其伴随症状的复合化合物铁(III)-吡嗪-2-醇-1-氧化物或其药学上可接受的盐。 2.根据权利要求1的用途的铁(III)的络合物,其包含至少一个式(I)的配体:其中箭头表示与一个或不同铁原子的配位键,R,R,R可以相同。选自以下组成的组:氢,卤素,任选取代的烷基,任选取代的烷氧基,任选取代的芳基,任选取代的烷氧基羰基和任选取代的氨基羰基,或R,R以及它们所键合的碳原子必要时,形成取代的5或6元饱和或不饱和环,其可任选含有一个或多个杂原子,或其药学上可接受的盐。 3.根据权利要求2的用途的铁(III)的络合物,其包含至少一个式(I)的配体:其中箭头表示与一个或不同铁原子的配位键,R,R,R和R可以是相同或不同的并且选自氢,氢,任选取代的烷基,卤素或R,R以及它们所连接的碳原子一起形成5元或6元碳环,或药学上其可接受的盐。 4.根据权利要求3使用的铁(III)的络合物,其包含至少一个式(I)的配体:其中箭头表示与一个或不同铁原子的配位键,R,R,R和R可以是相同或不同,然后选择

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