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POLYVALENT IMMUNIZING AND / OR THERAPEUTIC COMPOSITION FOR USE IN BACTERIAL INFECTIONS OR FOOD POISONING, IN PARTICULAR SALMONELLOSIS, METHOD OF OBTAINING THIS COMMUNITY COMMUNITY,
POLYVALENT IMMUNIZING AND / OR THERAPEUTIC COMPOSITION FOR USE IN BACTERIAL INFECTIONS OR FOOD POISONING, IN PARTICULAR SALMONELLOSIS, METHOD OF OBTAINING THIS COMMUNITY COMMUNITY,
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机译:用于特别是沙门氏菌病的细菌感染或食物中毒的多价免疫和/或治疗组合物,用于获得该社区的方法,
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摘要
1. A multivalent combined immunizing and / or anti-salmonellosis therapeutic composition comprising an inactivated Salmonella sp. Strain to which antibodies are linked, characterized in that the antibodies are selected so as to bind antigenic epitopes in the structures of repeating O-specific units in the main Salmonella bacteria groups that determine the principle of interaction with the host immune system, without blocking the epitopes that determine the recognition of the Salmonella serotype. 2. A composition according to claim 1, containing inactivated bacteria of the species enterica of the genus Salmonella: enterica, salamae, arizonae and / or diarizonae, houtenae and Indica. 3. The composition according to PP. 1 or 2, characterized in that the inactivated bacteria of the genus Salmonella belong to at least one of the following subgroups: from group 4 (B), in particular, serovars: Salmonella Typhimurium, Salmonella Typhimurium (for example, 1,4, [5], 12: i: -), Salmonella Agona, Salmonella Bredeney, Salmonella Heidelberg, Salmonella Indiana, Salmonella Saintpaul, Salmonella Brandenburg, Salmonella Agama, Salmonella Derby, Salmonella Stanley, Salmonella Paratyphi B, Salmonella Schleissheim, Salmonella Chester; from groups 6.7 and 8, (C1-C3), in particular, serovars: Salmonella Paratyphi C, Salmonella Infantis, Salmonella Hadar, Salmonella Mbandaka, Salmonella Livingstone, Salmonella Virchow, Salmonella Ohio, Salmonella Montevideo, Salmonella Tennessee, Salmonella Rissen, Salmonella Bareienburg, Salmonella Thompson, Sal monella Newport, Salmonella Kottbus, Salmonella Kentucky, Salmonella Albany, Salmonella Bovismorbificans, Salmonella Djugu, Salmonella Breanderup, Salmonella Jeruzalem, Salmonella Chester, Salmonella Goldcoast, Salmonella Braenderup; from groups 9 and 9.46 (D1-D2), in particular, serovars : Salmonella Enteritidis, Salmonella Panama, Salmonella Dublin, Salmonella Gallinarum, Salmonella Miami, Salmonella Sendai, Salmonella Wernigerode, Salmonella Typhi; from the group 3,10 [,] and 1,3,19 (E1-E4), in particular, serovars: Salmonella Give, Salmonella Anatum, Salmonella London, Salmonella Meleagridis, Salmonella Cambridge, Salmonella Minneapolis, Salmonella Simsbury, Salmonella Senftenberg, Salmonella Westerstede; from group 11 (F), in particular Salmonella Aberdeen; from group 13 (G1-G2), in particular , serovars: Salmonella Cubana, Salmonella Poona; from group 6.14 (H), in particular, serovars: Salm onella Heves, Salmonella Onderstepoort; from group 16 (I), in particular, serovars: Salmonella Brazil, Salmonella Hvittingfoss; from group 17 (J), in particular, Salmonella Berlin serovar; from group 18 (K), in particular, Salmonella serovar Ilia (O: 18); and from additional subgroups numbered 21, 28, 30, 35, 38, 39, 40, 41, 42, 43, 44, 45, 47, 48, and 50.4. The composition according to PP. 1 or 2, characterized in that the antibodies are isolated from rabbit serum immunized with Salmonella antigens. 5. The composition according to PP. 1 or 2, characterized in that said antibodies are isolated from the yolk of poultry eggs, in particular chicken eggs obtained from a bird immunized with Salmonella antigens. 6.
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