首页> 外国专利> METHOD OF PREDICTING RISK OF DEVELOPMENT OF ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH CORONARY HEART DISEASE AND TYPE 2 DIABETES WITH PRIOR CORONARY ARTERY STENTING

METHOD OF PREDICTING RISK OF DEVELOPMENT OF ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH CORONARY HEART DISEASE AND TYPE 2 DIABETES WITH PRIOR CORONARY ARTERY STENTING

机译:预测冠心病合并冠状动脉疾病和2型糖尿病患者不良心血管事件发生的方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to prediction of risk of unfavourable cardiovascular events in patients with ischemic heart disease (IHD) with type 2 diabetes mellitus (DM 2 type) after stenting coronary arteries. Invention can be used in cardiology, angiology, cardiac surgery, rehabilitation. For said purpose, immediately before stent, method includes determining in serum levels of markers of inflammation - lipoprotein-associated phospholipase A2 (Lp-PLA2) by enzyme immunoassay. Upon identifying in IHD patients with type 2 diabetes who underwent coronary stenting, Lp-PLA2 983 ng/ml or more, predict risk of adverse cardiovascular events.;EFFECT: invention allows to allocate priority group of IHD patients with type 2 diabetes who underwent coronary stenting, for organisation of follow-up with effective targeted interventions aimed at prevention of adverse cardiovascular events and in said patients to prevent high premature mortality.;1 cl, 3 tbl, 2 dwg, 2 ex
机译:发明领域本发明涉及在冠状动脉支架置入术中对患有2型糖尿病(DM 2型)的缺血性心脏病(IHD)患者不利的心血管事件的风险的预测。发明可用于心脏病学,血管学,心脏外科手术,康复。为了所述目的,在支架之前,方法包括通过酶免疫测定法测定血清中炎症标志物水平-脂蛋白相关的磷脂酶A2(Lp-PLA2)。在鉴定出患有冠状动脉支架置入术的IHD 2型糖尿病患者中,Lp-PLA2 983 ng / ml或更高时,可以预测心血管不良事件的风险。效果:本发明允许将接受冠状动脉置入术的IHD 2D糖尿病患者分配优先组支架置入术,用于组织随访,并采取有效的针对性干预措施,旨在预防不良心血管事件,并在所述患者中防止过早死亡。1cl,3 tbl,2 dwg,2 ex

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