SORBENT FOR SEPARATION OF OPTICAL ISOMERS OF SUBSTANCES AND ANALYSIS THEREOF IN BIOLOGICAL FLUIDS BY HPLC AND PREPARATION METHOD THEREOF

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to sorbents for high-performance liquid chromatography (HPLC), in particular to production of chemically modified sorbents. It is a sorbent based on silica gel with grafted through spacer hybrid chiral selector. This sorbent is obtained by modification of silica gel by epoxy groups, eremomycin and bovine serum albumin.;EFFECT: sorbent exhibits high enantioselectivity to various compounds, including while their analysis in biological fluids.;2 cl, 4 dwg, 2 tbl