METHOD OF DETECTING ACTIVE TUBERCULOSIS IN CHILDREN IN THE PRESENCE OF A CO-MORBIDITY

摘要

The present disclosure relates to a method of distinguishing active paediatric TB in the presence of a complicating factor, for example, latent TB and/or co-morbidities, such as those that present similar symptoms to TB in a child. The method employs a 42 gene signature and/or a 51 gene signature. The disclosure also relates to a gene signature employed in the method, a bespoke gene chip for use in the method and a disease risk score obtainable from the method.