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COMPOUND HAVING MELANIN PRODUCTION INHIBITORY ACTION, COLLAGEN PRODUCTION PROMOTING ACTION, AND WOUND HEALING PROMOTING ACTION
COMPOUND HAVING MELANIN PRODUCTION INHIBITORY ACTION, COLLAGEN PRODUCTION PROMOTING ACTION, AND WOUND HEALING PROMOTING ACTION
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机译:具有黑色素产生抑制作用,胶原产生促进作用和伤口愈合促进作用的化合物
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摘要
PROBLEM TO BE SOLVED: To provide a compound having a melanin production inhibitory action, a collagen production promoting action, and a wound healing promoting action.SOLUTION: According to the present invention, based on the experimental results, the compound represented by Chemical Formula I described below has a high inhibitory action, particularly to suppress the gene expression level of MMP-9 and the gene expression level of MITF in human skin fibroblasts. In addition to significantly suppress the gene expression level of MMP-9 and the gene expression level of MITFT, the compound causes an increase in amount of collagen produced in human fibroblasts and suppresses melanin in human fibroblasts.SELECTED DRAWING: Figure 1
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