Method of performing stimulus response test using artificial pluripotent stem cells derived from perinatal cells or tissues

摘要

A method is provided for performing a stimulus response test in iPSC or iPSC derived cells derived from perinatal cells taken from donors under no exposome conditions. In some embodiments, multiple donors are involved. In other embodiments, the iPSCs are differentiated. The use of induced pluripotent stem cells (iPSCs) derived from neonatal-derived cells makes it possible to largely eliminate the effects of aging and environmental exposure, and direct interaction between the stimulus and the test subject To allow analysis focused on. The use of iPSCs derived from cells derived from multiple donors has been shown to reduce the effects of different age and environmental effects compared to using other test materials To more precisely measure the role of genetic differences in determining responses to stimuli.