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Anti-dog IgE monoclonal antibody and anti-canine IgE monoclonal antibody heavy chain variable region and light chain variable region
Anti-dog IgE monoclonal antibody and anti-canine IgE monoclonal antibody heavy chain variable region and light chain variable region
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机译:抗狗IgE单克隆抗体和抗犬IgE单克隆抗体重链可变区和轻链可变区
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摘要
Problem to be Solved: The present invention is intended to provide a polynucleotide encoding the light-chain variable region and the heavy-chain variable region of an anti-dog IgE antibody; and an anti-dog IgE antibody containing these variable regions. Solution: The present invention is DNA encoding a heavy-chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 2 or 6 and DNA encoding a light-chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 4 or 8, and an anti-dog IgE monoclonal antibody which binds to dog IgE, containing these variable regions or a functional fragment thereof which binds to dog IgE.
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机译:要解决的问题:本发明旨在提供编码抗狗IgE抗体的轻链可变区和重链可变区的多核苷酸。以及含有这些可变区的抗狗IgE抗体。解决方案:本发明是编码由SEQ ID NO:2或6表示的氨基酸序列组成的重链可变区的DNA和编码由SEQ ID NO:2表示的氨基酸序列组成的轻链可变区的DNA。 4或8,以及与狗IgE结合的抗狗IgE单克隆抗体,其含有与狗IgE结合的这些可变区或其功能片段。
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