A method for inducing hepatic progenitor cells by a TGF- signaling inhibitor and / or Y-27632 and a production method thereof, and a method for producing hepatocytes from the hepatic progenitor cells

摘要

A method for hepatic differentiation of a stem cell selected from among embryonic stem cells, induced pluripotent stem cells or induced hepatic stem cells is presented. More specifically, a stem cell selected from among embryonic stem cells, induced pluripotent stem cells or induced hepatic stem cells is cultured for 1 to 4 weeks in the presence of a TGF-&bgr; inhibitor, whereby the hepatic differentiation of the stem cell is realized.