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Method for introducing selected molecule, apparatus for introducing selected molecule, and cell fusion method

机译:引入选择的分子的方法,引入选择的分子的设备和细胞融合方法

摘要

PROBLEM TO BE SOLVED: To provide a method for transferring a selected molecule into a target cell, by which the selected molecule can more efficiently be transferred than before, and a damage given to the target cell can be reduced, and to provide a selected molecule transfer device used for the same.SOLUTION: A method for transferring a selected molecule into a target cell or target tissue includes a step for bringing a transfer liquid which is a liquid containing the selected molecule into contact with the target cell or target tissue, and a step for bringing an aggregate comprising one or more selected from a group consisting of charged particles, excited atoms and excited molecules into contact with the transfer liquid and the target cell or the target tissue, wherein a capillary electrode is disposed on the opening portion side of a container for storing the transfer liquid apart from the transfer liquid; the capillary electrode has a jet opening of an aggregate precursor; the aggregate precursor is jetted from the jet opening of the capillary electrode to the transfer liquid; and, when contacting with the liquid, at least one portion of the aggregate precursor is changed into the aggregate.
机译:解决的问题:提供一种将选择的分子转移到靶细胞中的方法,通过该方法可以比以前更有效地转移选择的分子,并且可以减少对靶细胞的损害,并提供选择的分子解决方案:用于将选择的分子转移到靶细胞或靶组织中的方法包括使转移液与包含靶分子或靶组织的转移液接触的步骤,该转移液是包含选择的分子的液体,并且使包含选自带电粒子,受激原子和受激分子中的一种或多种的聚集体与转移液和靶细胞或靶组织接触的步骤,其中在开口部侧设置有毛细管电极用于将转移液体与转移液体分开存储的容器的;毛细管电极具有聚集前体的喷射口;聚集的前体从毛细管电极的喷射口喷射到转移液中。当与液体接触时,至少一部分聚集体前体变成聚集体。

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