Synthesis of optically pure l-/ d-lactide biomass organic guanidine catalyst method

摘要

A method of synthesizing optically pure L-/ D-lactide by Biomass organic guanidine catalyst method. In the method of the present invention, the creatinine biomass organic guanidine compound as a catalyst, L-/ D-lactic acid (mass content 90%) as a raw material, by using a reactive distillation under reduced pressure, L-/ D-lactide a to catalyst synthesis. The present invention, biomass organic guanidine catalysts CR to be used, have no toxicity and metal, is a fact not having also cytotoxic, the synthesized L-/ D-lactide, and optically pure after purification and (specific rotation of L- lactide is a [ ] 25D = -276~-280, the specific optical rotation of D- lactide, [ ] 25D = is 280), and, any metal and to have no, short reaction times, use less catalyst, and the process is simple, the operation is simple, having the benefits of equal is easy industrialization embodiment.BACKGROUND