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SYSTEMS AND METHODS FOR EXPRESSION-BASED DISCRIMINATION OF DISTINCT CLINICAL DISEASE STATES IN PROSTATE CANCER
SYSTEMS AND METHODS FOR EXPRESSION-BASED DISCRIMINATION OF DISTINCT CLINICAL DISEASE STATES IN PROSTATE CANCER
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机译:前列腺癌中基于表达的区别性临床疾病状态的鉴别系统和方法
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摘要
A system for expression-based discrimination of distinct clinical disease states in prostate cancer is provided that is based on the identification of sets of gene transcripts, which are characterized in that changes in expression of each gene transcript within a set of gene transcripts can be correlated with recurrent or non-recurrent prostate cancer. The Prostate Cancer Prognostic system provides for sets of “prostate cancer prognostic” target sequences and further provides for combinations of polynucleotide probes and primers derived there from. These combinations of polynucleotide probes can be provided in solution or as an array. The combination of probes and the arrays can be used for diagnosis. The invention further provides further methods of classifying prostate cancer tissue.
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