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Genetic susceptibility variants associated with cardiovascular disease

机译:与心血管疾病有关的遗传易感性变异

摘要

The invention relates to methods of diagnosing susceptibility to cardiovascular disease, including coronary artery disease. MI, abdominal aorta aneurysm, intracranial aneurysm restenosis and peripheral arterial disease, by assessing the presence or absence of alleles of certain polymorphic markers found to be associated with cardiovascular disease. The invention further relates to kits encompassing reagents for assessing such markers, and methods for assessing the probability of response to therapeutic agents and methods using such markers.
机译:本发明涉及诊断对包括冠状动脉疾病在内的心血管疾病的易感性的方法。心肌梗死,腹主动脉瘤,颅内动脉瘤再狭窄和周围动脉疾病,通过评估是否存在某些与心血管疾病有关的多态性标记等位基因来进行。本发明进一步涉及包含用于评估此类标记物的试剂的试剂盒,以及用于评估对治疗剂反应的可能性的方法和使用此类标记物的方法。

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