starch compounds as modulators of rort t and uses thereof

摘要

abstract starch compounds are disclosed that have a formula represented by the following: and wherein cy1, cy2, n1, n2, r1a, r1b, r2, r3, r4, r5, and r6 are as described herein. the compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus- Host disease. "Starch compounds as modulators of ror? t and uses thereof". starch compounds having a formula represented by the following are described: and wherein cy1, cy2, n1, n2, r1a, r1b, r2, r3, r4, r5 and r6 are as described herein. The compounds may be prepared as pharmaceutical compositions and may be used for the prevention and treatment of a variety of conditions in mammals, including humans including, by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft versus host disease. 1049-1-169pct 2 1049-1-169pct 1