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cancer screening method iii, cervical, ovarian, liver, colon, breast, oral, and endometrial cancer screening methods and sarcoma screening method

机译:癌症筛查方法iii,宫颈癌,卵巢癌,肝癌,结肠癌,乳腺癌,口腔癌和子宫内膜癌的筛查方法和肉瘤筛查方法

摘要

Disclosed in the present invention is a method for screening cancer, comprising the following steps: (1) providing a specimen to be detected; (2) detecting the methylation status of CpG sequence of at least one target gene which is at least one of ADRA1D, AJAP1, HS3ST2, MAGI2, POU4F2, POU4F3, PTGDR, SOX17 and SYT9 in genomic DNA of the specimen; (3) determining whether cancer or precancerous lesions are present in the specimen according to the methylation status of at least one target gene.
机译:本发明公开了一种癌的筛查方法,其包括以下步骤:(1)提供要检测的标本; (2)检测标本基因组DNA中至少一个靶基因的CpG序列的甲基化状态,所述靶基因是ADRA1D,AJAP1,HS3ST2,MAGI2,POU4F2,POU4F3,PTGDR,SOX17和SYT9中的至少一种。 (3)根据至少一种靶基因的甲基化状态,确定样品中是否存在癌变或癌前病变。

著录项

  • 公开/公告号BR112015004423A2

    专利类型

  • 公开/公告日2017-08-08

    原文格式PDF

  • 申请/专利权人 NATIONAL DEFENSE MEDICAL CENTER;

    申请/专利号BR20151104423

  • 发明设计人 LAI HUNGCHENG;

    申请日2012-08-31

  • 分类号C12Q1/68;

  • 国家 BR

  • 入库时间 2022-08-21 13:40:16

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