gene expression biomarkers and their use for diagnostic and prognostic application in patients potentially in need of hdac inhibitor treatment

摘要

Patent Summary: "Biomarkers of gene expression and their use for diagnostic and prognostic application in patients potentially in need of hdac inhibitor treatment". The present invention relates to the use of one or more genes selected from the group comprising zfp64, dpp3, ccdc43, hist2h4a / b, kdelc2 and micall1 as biomarkers for the treatment of hdac inhibitor. The expression and / or alteration of the aforementioned genes are preferably determined by their corresponding mRNA or one or more proteins expressed by the aforementioned genes. 1/1