methods of treating a patient diagnosed with type 1 diabetes, methods of reducing, suppressing, attenuating, or inhibiting one or more symptoms associated with t1d, and methods of treating a patient who is at risk for t1d

摘要

The present disclosure relates to methods for treating type 1 (t1d) diabetes using a glucagon receptor blocking agent. more specifically, the present disclosure relates to methods for treating t1d using substantially lower doses of insulin supplementation, or even in the absence of insulin supplementation, using antigen binding and antagonizing proteins, for example, fully human antibodies that specifically bind and antagonize human glucagon receptor function.