vaccine compositions, immunogenic composition, method for expression of the above-mentioned hpv-hbsag chimeric antigens, pharmaceutical composition, method for eliciting protective antibody response to antigenic composition and / or cytotoxic T cell response, use of the above-mentioned antigenic formulations.

摘要

The invention describes a vaccine compositions comprising chimeric fusions of the HPV antigens with viral or bacterial proteins conferring enhanced immunogenicity useful for Hepatitis B virus as well as human papillomavirus (HPV) infections.