Use of an immunoglobulin with enhanced binding affinity to fc-gamma-riib and reduced binding affinity to fc-gamma-riiia for the preparation of a medicament

摘要

The present invention relates to immunoglobulins that bind Fc³Rllb+ cells and coengage the antigen on the cell's surface and an Fc³Rllb on the cell's surface, methods for their generation, and methods for using the immunoglobulins.