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Pharmaceutical composition comprising substituted benzenesulfonamide compounds for use in treating systemic lupus erythematosus, lupus nephritis or sjogren's syndrome
Pharmaceutical composition comprising substituted benzenesulfonamide compounds for use in treating systemic lupus erythematosus, lupus nephritis or sjogren's syndrome
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机译:包含取代的苯磺酰胺化合物的药物组合物,用于治疗系统性红斑狼疮,狼疮肾炎或干燥综合征
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摘要
This invention pertains to methods of treating systemic lupus erythematosus, lupus nephritis or Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti-apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl-x L .
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