ULTRASONIC CONTRAST AGENT DETECTON AND IMAGING BY LOW FREQUENCY MANIPULATION OF HIGH FREQUENCY SCATTERING PROPERTIES

摘要

This invention relates to methods and systems for ultrasonic detection and imaging of contrast agents located in soft tissue or tissue fluids. Background Ultrasound contrast agents are typically made as solutions of micro gas bubbles or nano lipid particles. The gas bubbles typically show strong and nonlinear scattering of the ultrasound, a phenomenon that is used to differentiate the contrast agent signal from the tissue signal