METHOD FOR THE FRACTIONATION OF KNOTWOOD EXTRACT AND USE OF A LIQUID-LIQUID EXTRACTION FOR PURIFICATION OF KNOTWOOD EXTRACT

摘要

The invention relates to a method for the fractionation of knotwood extract,which has been obtained by extractionof knotwood with a hydrophilic solvent. The hydrophilic extract is extractedwith a lipophilic solvent to remove lipophilic impuri-ties.The invention also relates to the use of a liquid-liquid extraction for thepurification of hydrophilic knotwood extract. Thepresent process provides a purified knotwood extract, which contains more than90 % lignans, flavonoids and stilbenes and lessthan 10 % impurities selected from resin acids, fatty acids, sterols,juvabiones, triglycerides and combinations thereof.