The present invention concerns a bacteriophage able to lyse Klebsiella pneumoniae expressing a CPSKKBO-4 capsular polysaccharide, including but not limited to, strains of sequence type ST258-2, the major genotype of Klebsiella pneumoniae carbapenemase (KPC) producing strains, and related uses thereof in surface sanitization, colonization prevention, decolonization of carriers, diagnosis and therapy.
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