A multi-electrode renal artery ablation catheter, comprising a regulating component (100) for regulating nerves, a conveying member (201) for conveying the regulating conditioning component (100) to a position of a nerve, and a sheath (301). The regulating component (100) comprises a plurality of electrodes (101) for transferring regulating energy to the nerve and a carrier member (102) for carrying a plurality of electrodes (101). The carrier member (102) has a first shape and a second shape. The regulating component (100) is adapted to move in a blood vessel when the carrier member is in the first shape. When in the second shape, at least one of the electrodes (101) is at a position suitable for transferring the regulating energy to the nerve. The sheath (301) is sleeved over the conveying member (201) and is slidable along the conveying member (201) and is sleeved over or disengaged from the regulating component (100). A guide wire channel (500) is arranged within the multi-electrode renal artery ablation catheter, and the guide wire channel (500) penetrates throughout the entire multi-electrode renal artery ablation catheter. The carrier member (102) can be switched between the first shape and second shape by means of a solo action of the sheath (301) or a guide wire, or by a combined action of the sheath (301) and the guide wire.
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