CRYSTALLINE OLAPARIB SOLVATES WITH ACETONE, 2-PROPANOL AND/OR METHYL ETHYL KETONE

摘要

The invention relates to solvated crystalline forms of olaparib of formula I, with the systematic name 4-[(3-[(4-cyclopropylcarbonyl)piperazin-4-yl]carbonyl)-4-fluorophenyl]methyl(2H)- phtalazin-1-one, a method of their preparation and use for the production of a drug form. The used solvent is acetone, 2-propanol, or methyl ethyl ketone, or a mixture of the said solvents can be used. Another object is a preparation method of olaparib solvate.