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AMPK AZAINDOLE DERIVATIVE HAVING AMPK-ACTIVATING EFFECT
AMPK AZAINDOLE DERIVATIVE HAVING AMPK-ACTIVATING EFFECT
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机译:AMPK氮杂吲哚衍生物具有AMPK激活作用
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摘要
A compound useful as an AMPK activator. expression: Wherein X is selected from substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkyl , Substituted or unsubstituted cycloalkenyl or substituted or unsubstituted heterocyclyl, R 1 is hydrogen, halogen, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted Substituted or unsubstituted alkylsulfonyl, substituted or unsubstituted alkylsulfonyl, or substituted or unsubstituted alkyloxycarbonyl, substituted or unsubstituted alkylsulfonyl, substituted or unsubstituted alkylsulfonyl, and, R 2 is a halogen, a substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted Cyclo alkyl, and substituted or unsubstituted cycloalkenyl, substituted or unsubstituted heterocyclyl, R 3 is an alkyl, a substituted or unsubstituted ring, halogen, hydroxy, cyano, nitro, carboxy, substituted or beach Substituted or unsubstituted alkyl, alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted heterocycle And R 4 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, etc. Or a pharmaceutically acceptable salt thereof.
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