SITAGLIPTIN INTERMEDIATE METHOD OF SYNTHESIZING THE SITAGLIPTIN INTERMEDIATE AND METHOD OF SYNTHESIZING SITAGLIPTIN USING THE SITAGLIPTIN INTERMEDIATE

摘要

Disclosed is an intermediate compound of sitagliptin which has a molecular structure represented by chemical formula 1. The use of the intermediate compound of sitagliptin enables production of sitagliptin compounds which are used as dipeptidyl peptidase-4 (DPP-4) inhibitors in a cost effective and eco-friendly manner, without using expensive coupling agents.