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AMPHIPHILIC CHITOSAN DERIVATIVE AND DRUG CARRIER CONTAINING SAME

机译:两性壳聚糖衍生物和药物载体相同

摘要

The present invention relates to an amphiphilic chitosan derivative and an emulsion material comprising the same. The chitosan derivative of the present invention is modified with a carboxymethyl group and a hexanoyl group and thus has amphiphilic properties. The chitosan derivative has excellent emulsifying properties and thus can be used as a material for a drug carrier. The chitosan derivative is represented by chemical formula 1. R_1 is CH_2COOH or H. R_2 is CO(CH_2)_4CH_3, CH_2COOH, COCH_3 or H. M represents an integer of 10-1,000. The drug carrier has a formulation of liposome, a micelle, emulsion, or a nanoparticle.;COPYRIGHT KIPO 2017
机译:两亲性壳聚糖衍生物及其乳液材料本发明涉及两亲性壳聚糖衍生物及其乳液材料。本发明的壳聚糖衍生物被羧甲基和己酰基改性,因此具有两亲性。壳聚糖衍生物具有优异的乳化性能,因此可以用作药物载体的材料。壳聚糖衍生物由化学式1表示。R_1为CH_2COOH或H。R_2为CO(CH_2)_4CH_3,CH_2COOH,COCH_3或H。M表示10-1,000的整数。药物载体具有脂质体,胶束,乳剂或纳米颗粒的制剂。; COPYRIGHT KIPO 2017

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