Self-assembled nanostructures of elastin and resilin-based block copolypeptides with stimuli responsiveness and resilience for drug delivery system tissue engineering and regenerative medicine and methods of preparing thereof

摘要

The present invention relates to drug delivery, tissue engineering, self-assembled nanostructures and methods for their preparation and application of the block based on elastin and re stricken with a reactive stimulus and elasticity for regenerative medicine polypeptide. Was formed in the assembled micelle structure, the triple-block poly hydrogel prepared using peptayideueul is in accordance with the temperature stimulation reversible sol-the dual block polypeptide is a reversible variable-self, depending on the temperature stimulation gel or gel-sol becomes a transition made, it can be seen that mechanical strength is enhanced by the glass tyrosine term chemical crosslinking. The present invention having such excellent properties could be used as a drug carrier, a support for tissue engineering and tissue or organ regeneration kit.