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Iodine radioisotope-labeled azide tracers preparation method thereof and compositions containing the same as an active ingredient for use Iodine radioisotope-labeling or medical diagnosis
Iodine radioisotope-labeled azide tracers preparation method thereof and compositions containing the same as an active ingredient for use Iodine radioisotope-labeling or medical diagnosis
The present invention relates to a radioactive iodine-labeled azide compound, a process for producing the same, and a radioactive iodine label or a medical diagnostic composition containing the same as an active ingredient. The radioactive iodine-labeled azide compound according to the present invention is a radioactive iodine labeled with radioactive iodine at a rapid reaction rate and a high radiochemical yield through copper-free click reaction of biomolecules or nanoparticles containing DBCO (dibenzocyclooctane) Can be used for radioiodine labeling or medical diagnosis of biomolecules or nanoparticles because they are stable in vivo, are rapidly absorbed and accumulated in liver and kidney, exhibit fast in vitro excretion rate.;
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