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COMPOUNDS AND METHODS FOR PEG METABOLITE AND PEG BREAKDOWN PRODUCT ASSAYS
COMPOUNDS AND METHODS FOR PEG METABOLITE AND PEG BREAKDOWN PRODUCT ASSAYS
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机译:PEG代谢物和PEG分解产物测定的化合物和方法
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摘要
Disclosed herein are compounds and methods for identifying and quantifying a metabolite or breakdown product of PEG. A sample may be assayed for PEG metabolites or breakdown products using liquid chromatography combined with mass spectrometry. Derivatization of the PEG metabolites or breakdown products within the sample with pentaflurobenzoyl chloride in conjunction with negative chemical ionization mode liquid chromatography optimizes the assay.
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