CYCLIC PEPTIDE NMP INITIATOR AND METHOD FOR PRODUCING MULTIBLOCK TYPE POLYMER

摘要

PROBLEM TO BE SOLVED: To provide a new synthesis method that makes it possible to produce conveniently a multiblock type polymer composed of an artificial peptide and a vinyl polymer.;SOLUTION: A cyclic peptide NMP initiator is used to polymerize a vinyl monomer. Each X1 may be the same or different to represent an amino acid or a derivative thereof (n is 1-20), S1 and S2 are spacer groups (l and m are 0-4), X2 is an amino acid or an amino acid derivative having a side chain functional group that can react with an amino group or a carboxyl group, and Z is a compound that can generate a nitroxyl radical.;SELECTED DRAWING: Figure 1;COPYRIGHT: (C)2018,JPO&INPIT