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T-CELL REGULATION IN T-CELL MEDIATED DISEASES BY REDUCING PATHOGENIC FUNCTION OF TH17 IN A HUMAN SUBJECT THROUGH TREATMENT WITH A NITROXIDE
T-CELL REGULATION IN T-CELL MEDIATED DISEASES BY REDUCING PATHOGENIC FUNCTION OF TH17 IN A HUMAN SUBJECT THROUGH TREATMENT WITH A NITROXIDE
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机译:通过减少人为治疗氮氧化物对人的TH17致病作用,调节T细胞介导的疾病中的T细胞调节
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摘要
A method of reducing pathogenic T-helper cell activity in a human subject in need thereof is disclosed. The method comprises administering to the human subject, known to have a condition mediated by one or more differentiated T-helper cells responsive to Cd51, an effective amount of a nitroxide antioxidant, where the nitroxide antioxidant increases Cd51 expression, thereby reducing pathogenic T-helper cell activity. In some embodiments, the condition is an autoimmune disease.
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