USE OF IL-31 MONOCLONAL ANTIBODIES FOR ANTAGONIZING SIGNAL TRANSDUCTION IN DORSAL ROOT GANGLION CELLS

摘要

Use of antagonists to IL-31 are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such antagonists include antibodies and fragments, derivative, or variants thereof. Symptoms such as pain, tingle, sensitization, tickle associated with neuropathies are ameliorated.