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Use of monosaccharide-like glycylated sugar alcohol compositions for designing and developing anti-diabetic drugs

机译:单糖样糖基化糖醇组合物在设计和开发抗糖尿病药物中的用途

摘要

This invention is related to a novel sugar-like chemical composition and its use for diabetes therapy. Particularly, the present invention teaches the use of monosaccharide-like glycylated sugar alcohol compounds to block or reduce sugar absorption in diabetes patients, so as to prevent the risk of hyperglycemia symptoms. Glycylation of sugar alcohols is a totally novel reaction that has never been reported before. Therefore, the novelty of the present invention is that for the first time glycylated sugar alcohols not only was found but also was found to be useful for treating Diabetes mellitus. In addition, the present invention teaches a method for producing these glycylated sugar alcohols. In sum, the present invention includes not only a kind of novel sugar-like chemical compositions and its use for treating diabetes but also a state-of-the-art protocol and methodology for producing such a novel composition via glycylation of sugars and sugar alcohols.
机译:本发明涉及新型糖样化学组合物及其在糖尿病治疗中的用途。特别地,本发明教导了使用单糖样糖基化糖醇化合物来阻断或减少糖尿病患者中糖的吸收,从而防止高血糖症状的风险。糖醇的糖基化是一个全新的反应,从未有过报道。因此,本发明的新颖性在于,首次不仅发现了糖基化的糖醇,而且发现其可用于治疗糖尿病。另外,本发明教导了生产这些糖基化糖醇的方法。总之,本发明不仅包括一种新型的糖样化学组合物及其在治疗糖尿病中的用途,而且还包括通过糖和糖醇的糖基化生产这种新型组合物的最新技术方案和方法学。 。

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