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Diagnosis and treatment of chronic obstructive pulmonary disease (COPD) based on elevated levels of extracellular H3 protein
Diagnosis and treatment of chronic obstructive pulmonary disease (COPD) based on elevated levels of extracellular H3 protein
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机译:基于细胞外H3蛋白水平升高的慢性阻塞性肺疾病(COPD)的诊断和治疗
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摘要
Provided is a method for diagnosing and/or staging COPD based on detection of one or more histone proteins. In some embodiments, the histone protein is an H3.3 protein comprising a post-translational modification. In some embodiments, the histone protein is H2B, H3, H3.3 or H4. Kits for practicing the methods of diagnosis and/or staging are provided as well. Further provided is a method for treating COPD.
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