Benzosultamas and the like

摘要

Active compounds as fungicides, More specifically benzosultamas and analogues thereof, processes and Intermediates for their Preparation and use as Fungicide Active compounds.Particularly in the form of Fungicide compositions. Methods for Control of fungi fitopatogénicos in plants using the compounds and compositions containing same.Claim 1: wherein is a compound of formula (1), where a is a Ring Heterociclilo bicyclic FUSED partially saturated or unsaturated 9,10 or 11 Member comprising at least one nitrogen Atom and between 0 and 4 additional heteroatoms selected independently of the list consists of N,O and S; Z is selected from the group consisting of hydrogen Atom, Atom c₁₋₈ Halogen, alkyl,C₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₂₋₈ - alquinilo,C₂₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl, c₄₋₇ - cicloalquenilo, hydroxyl, c₁₋₈ alkoxy -,C₁₋₈ - up to 9 halógenoalcoxi Halogen Atoms can be equal or different, aryl, heterociclilo, Formilo, alquilcarbonilo c₁₋₈ - (hydroxyimino) c₁₋₈ alkyl,(c₁₋₈ - alcoxiimino) c₁₋₈ alkyl, carboxyl, c₁₋₈ - alcoxicarbonilo, carbamoilo, c₁₋₈ - alquilcarbamoilo alquilcarbamoilo c₁₋₈ -, di -, amino -, c₁₋₈ alquilamino alquilamino c₁₋₈ -, di -, sulfanilo,C₁₋₈ - alquilsulfanilo, c₁₋₈ - alquilsulfinilo, c₁₋₈ - alquilsulfonilo, c₁₋₆ - trialquilsililo, cyano and nitro, where z is optionally substituted; n is 0, 1, 2, 3 or 4; and P is 0, 1, 2, 3,4 or 5; X is selected independently from the group consisting of c₁₋₈ Halogen Atom, alkyl,C₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₂₋₈ - alquinilo,C₂₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl, c₄₋₇ - cicloalquenilo, hydroxyl, c₁₋₈ alkoxy -,C₁₋₈ - up to 9 halógenoalcoxi Halogen Atoms can be equal or different, aryl, heterociclilo, Formilo, alquilcarbonilo c₁₋₈ - (hydroxyimino) c₁₋₈ alkyl,(c₁₋₈ - alcoxiimino) c₁₋₈ alkyl, carboxyl, c₁₋₈ - alcoxicarbonilo, carbamoilo, c₁₋₈ - alquilcarbamoilo alquilcarbamoilo c₁₋₈ -, di -, amino -, c₁₋₈ alquilamino alquilamino c₁₋₈ -, di -, sulfanilo,C₁₋₈ - alquilsulfanilo, c₁₋₈ - alquilsulfinilo, c₁₋₈ - alquilsulfonilo, c₁₋₆ - trialquilsililo, c₁₋₆ - trialquilsilil - c₁₋₆ alkyl, cyano and NitroWhere each X is optionally substituted; and selected independently from the group consisting of c₁₋₈ Halogen Atom, alkyl,C₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₂₋₈ - alquinilo,C₂₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl, c₄₋₇ - cicloalquenilo, hydroxyl, c₁₋₈ alkoxy -,C₁₋₈ - up to 9 halógenoalcoxi Halogen Atoms can be equal or different, aryl, heterociclilo, Formilo, c₁₋₈ - (hydroxyimino) c₁₋₈ alquilcarbonilo, alkyl, carboxyl,(c₁₋₈ - alcoxiimino) c₁₋₈ alkyl, c₁₋₈ - alcoxicarbonilo, carbamoilo, c₁₋₈ - alquilcarbamoilo alquilcarbamoilo c₁₋₈ -, di -, amino -, c₁₋₈ alquilamino alquilamino c₁₋₈ -, di -, sulfanilo, c₁₋₈ - alquilsulfanilo,C₁₋₈ - alquilsulfinilo, c₁₋₈ - alquilsulfonilo, c₁₋₆ - trialquilsililo, cyano and NitroWhere each and is optionally substituted; l¹ is cr¹ᵃr¹ᵇ where: r¹ᵃ and r¹ᵇ are selected independently from the group consisting of hydrogen Atom, halogen Atom,C₁₋₈ alkyl, c₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₂₋₈ - alquinilo,C₂₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl,C₃₋₇ - up to 9 halógenocicloalquilo Halogen Atoms can be equal or different, c₃₋₇ - cicloalquil - c₁₋₈ alkyl, aryl, aryl alkyl c₁₋₈, heterociclilo,Heterociclil - c₁₋₈ hydroxyl, alkyl, alkoxy and c₁₋₈ c₁₋₈ - 9 - halógenoalcoxi comprising Halogen Atoms can be equal or different,Where each of r¹ᵃ and r¹ᵇ is optionally substituted, or r¹ᵃ and r¹ᵇ along with the carbon Atom to which they are United to form a carbociclo heterocycle or saturated or partially saturated with 3, 4,5 or 6 members optionally replaced that comprises at least one heteroatom selected from the list that consists of N, o and SOr r¹ᵃ and r¹ᵇ along with the carbon Atom to which they are United to form a Bicyclo [m¹.m².0] - c₆₋₁₁ partially saturated or unsaturated alkyl, substituted or non substituted where M + m = - 1 and m¹ between 4 and 9Or r¹ᵃ and r¹ᵇ along with the carbon Atom to which they are United to form a heterobiciclo [m¹.m².0] - c₆₋₁₁ partially saturated or unsaturated alkyl, substituted or non substituted comprising between 1 and 4 heteroatoms selected independently of the list consists of N, o and SWhere M + m = - 1 and m¹ between 4 and 9, or r¹ᵃ and r¹ᵇ along with the carbon Atom to which they are United to form a spiro [n¹.C₅₋₁₁] - N - alkyl or partially saturated unsaturated, replaced or not replaced where n¹ - 2 and n¹ + N = 4 and 10,Or r¹ᵃ and r¹ᵇ along with the carbon Atom to which they are United to form a heteroespiro [n¹.C₅₋₁₁] - N - alkyl or partially saturated unsaturated, replaced or not replaced comprising between 1 and 4 heteroatoms selected independently of the list consists of N, o and SWhere n¹ - 2 and n¹ + N = 4 and 10, or r¹ᵃ and r¹ᵇ along with the carbon Atom to which they are United to form a group metilideno replaced or not replaced; L² is a direct link, cr²ᵃr²ᵇ, C (= o),Or, nr²ᶜ, c = N - or²ᵈ, S, S (OR) or SO₂ where r²ᵃ and r²ᵇ are selected independently from the group consisting of hydrogen Atom, Atom c₁₋₈ Halogen, alkyl,C₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₂₋₈ - alquinilo,C₂₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl,C₃₋₇ - up to 9 halógenocicloalquilo Halogen Atoms can be equal or different, c₃₋₇ - cicloalquil - c₁₋₈ alkyl, aryl, aryl alkyl c₁₋₈, heterociclilo,Heterociclil - c₁₋₈ hydroxyl alkyl, alkoxy, c₁₋₈ -, 9 - c₁₋₈ halógenoalcoxi comprising Halogen Atoms can be equal or different, c₂₋₈ - alqueniloxi,C₂₋₈ - up to 9 halógenoalqueniloxi Halogen Atoms can be equal or different, c₃₋₈ - alquiniloxi,C₃₋₈ - up to 9 halógenoalquiniloxi Halogen Atoms can be equal or different, c₃₋₇ - cicloalcoxi,C₃₋₇ - up to 9 halógenocicloalcoxi Halogen Atoms can be equal or different, c₃₋₇ - cicloalquil c₁₋₈ - alkoxy -, ariloxi, c₁₋₈ aryl alkoxy -, heterocicliloxi,Heterociclil - c₁₋₈ - alkoxy - alkoxy - and heterociclil c₁₋₈ bicyclic FUSED partially saturated or unsaturated 9,10 or 11 members comprising between 1 and 5 heteroatoms selected independently of the list consists of N, o and S, where each of r²ᵃ and r²ᵇ is optionally substituted,Or r²ᵃ and r²ᵇ along with the carbon Atom to which they are United to form a carbociclo or saturated or partially saturated Heterocycles, replaced or not replaced 3, 45 or 6 members comprising at least one heteroatom selected from the list that consists of N, o and S, or r²ᵃ and r²ᵇ along with the carbon Atom to which they are United to form a Bicyclo [m¹.m².0] - c₆₋₁₁ partially saturated or unsaturated alkyl, substituted or non substituted where M + m = - 1 and m¹ between 4 and 9Or r²ᵃ and r²ᵇ along with the carbon Atom to which they are United to form a heterobiciclo [m¹.m².0] - c₆₋₁₁ partially saturated or unsaturated alkyl, substituted or non substituted comprising between 1 and 4 heteroatoms selected independently of the list consists of N, o and SWhere M + m = - 1 and m¹ between 4 and 9, or r²ᵃ and r²ᵇ along with the carbon Atom to which they are United to form a spiro [n¹.C₅₋₁₁] - N - alkyl or partially saturated unsaturated, replaced or not replaced where n¹ - 2 and n¹ + N = 4 and 10,Or r²ᵃ and r²ᵇ along with the carbon Atom to which they are United to form a heteroespiro [n¹.C₅₋₁₁] - N - alkyl or partially saturated unsaturated, replaced or not replaced comprising between 1 and 4 heteroatoms selected independently of the list consists of N, o and S- Where n¹ n¹ + N = 2 and between 4 and 10Or r²ᵃ and r²ᵇ along with the carbon Atom to which they are United to form a group metilideno replaced or not replaced; r²ᶜ is selected from the group consisting of hydrogen Atom,C₁₋₈ alkyl, c₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₃₋₈ - alquinilo,C₃₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl,C₃₋₇ - up to 9 halógenocicloalquilo Halogen Atoms can be equal or different, c₃₋₇ - cicloalquil - c₁₋₈ alkyl, Formilo, c₁₋₈ - alquilcarbonilo,C₁₋₈ - up to 9 halógenoalquilcarbonilo Halogen Atoms can be equal or different, c₁₋₈ - alcoxicarbonilo,C₁₋₈ - up to 9 halógenoalcoxicarbonilo Halogen Atoms can be equal or different, c₁₋₈ - alquilsulfonilo,C₁₋₈ - up to 9 halógenoalquilsulfonilo Halogen Atoms can be equal or different, arilsulfonilo c₁₋₈, aryl, aryl alkyl, alkyl - and heterociclilo heterociclil c₁₋₈,Where each of r²ᶜ is optionally substituted; r²ᵈ is selected from the group consisting of hydrogen Atom, alkyl c₁₋₈,C₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₃₋₈ - alquinilo,C₃₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl,C₃₋₇ - up to 9 halógenocicloalquilo Halogen Atoms can be equal or different, c₃₋₇ - cicloalquil - c₁₋₈ alkyl, aryl, aryl alkyl c₁₋₈,Heterociclilo and heterociclil c₁₋₈ alkyl -, where each of r²ᵈ is optionally substituted; l³ is a direct link, cr³ᵃr³ᵇ, C (= o), or, nr³ᶜ, c = N - or³ᵈ, S,S (OR) or SO₂ on condition that L² - l³ do not represent a peroxy Group [OR], where r³ᵃ and r³ᵇ are selected independently from the group consisting of hydrogen Atom,C₁₋₈ Halogen Atom, alkyl, c₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₂₋₈ - alquinilo,C₂₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl,C₃₋₇ - up to 9 halógenocicloalquilo Halogen Atoms can be equal or different, c₃₋₇ - cicloalquil - c₁₋₈ alkyl, aryl, aryl alkyl c₁₋₈, heterociclilo,Heterociclil - c₁₋₈ hydroxyl alkyl, alkoxy, c₁₋₈ -, 9 - c₁₋₈ halógenoalcoxi comprising Halogen Atoms can be equal or different c₂₋₈ - alqueniloxi,C₂₋₈ - up to 9 halógenoalqueniloxi Halogen Atoms can be equal or different, c₃₋₈ - alquiniloxi,C₃₋₈ - up to 9 halógenoalquiniloxi Halogen Atoms can be equal or different, c₃₋₇ - cicloalcoxi,C₃₋₇ - up to 9 halógenocicloalcoxi Halogen Atoms can be equal or different, c₃₋₇ - cicloalquil c₁₋₈ - alkoxy -, ariloxi, c₁₋₈ aryl alkoxy -, heterocicliloxi,Heterociclil - c₁₋₈ - alkoxy - alkoxy - and heterociclil c₁₋₈ bicyclic FUSED partially saturated or unsaturated 9,10 or 11 members comprising between 1 and 5 heteroatoms selected independently of the list consists of N, o and S, where each of r³ᵃ and r³ᵇ is optionally substituted,Or where r³ᵃ and r³ᵇ along with the carbon Atom to which they are United to form a carbociclo or saturated or partially saturated Heterocycles, replaced or not replaced 3, 45 or 6 members comprising at least one heteroatom selected from the list that consists of N, o and S, or r³ᵃ and r³ᵇ along with the carbon Atom to which they are United to form a Bicyclo [m¹.m².0] - c₆₋₁₁ partially saturated or unsaturated alkyl, substituted or non substituted where M + m = - 1 and m¹ between 4 and 9Or r³ᵃ and r³ᵇ along with the carbon Atom to which they are United to form a heterobiciclo [m¹.m².0] - c₆₋₁₁ partially saturated or unsaturated alkyl, substituted or non substituted comprising between 1 and 4 heteroatoms selected independently of the list consists of N, o and SWhere M + m = - 1 and m¹ between 4 and 9, or r³ᵃ and r³ᵇ along with the carbon Atom to which they are United to form a spiro [n¹.C₅₋₁₁] - N - alkyl or partially saturated unsaturated, replaced or not replaced where n¹ - 2 and n¹ + N = 4 and 10,Or r³ᵃ and r³ᵇ along with the carbon Atom to which they are United to form a heteroespiro [n¹.C₅₋₁₁] - N - alkyl or partially saturated unsaturated, replaced or not replaced comprising between 1 and 4 heteroatoms selected independently of the list consists of N, o and S- Where n¹ n¹ + N = 2 and between 4 and 10Or r³ᵃ and r³ᵇ along with the carbon Atom to which they are United to form a group metilideno replaced or not replaced; r³ᶜ is selected from the group consisting of hydrogen Atom,C₁₋₈ alkyl, c₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₃₋₈ - alquinilo,C₃₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl,C₃₋₇ - up to 9 halógenocicloalquilo Halogen Atoms can be equal or different, c₃₋₇ - cicloalquil - c₁₋₈ alkyl, a Formilo, c₁₋₈ - alquilcarbonilo,C₁₋₈ - up to 9 halógenoalquilcarbonilo Halogen Atoms can be equal or different, c₁₋₈ - alcoxicarbonilo,C₁₋₈ - up to 9 halógenoalcoxicarbonilo Halogen Atoms can be equal or different, c₁₋₈ - alquilsulfonilo,C₁₋₈ - up to 9 halógenoalquilsulfonilo Halogen Atoms can be equal or different, arilsulfonilo c₁₋₈, aryl, aryl alkyl, alkyl - and heterociclilo heterociclil c₁₋₈,Where each of r³ᶜ is optionally substituted; r³ᵈ is selected from the group consisting of hydrogen Atom, alkyl c₁₋₈,C₁₋₈ - up to 9 halógenoalquilo Halogen Atoms can be equal or different, c₂₋₈ - alquenilo,C₂₋₈ - up to 9 halógenoalquenilo Halogen Atoms can be equal or different, c₃₋₈ - alquinilo,C₃₋₈ - up to 9 halógenoalquinilo Halogen Atoms can be equal or different, c₃₋₇ - cycloalkyl,C₃₋₇ - up to 9 halógenocicloalquilo Halogen Atoms can be equal or different, c₃₋₇ - cicloalquil - c₁₋₈ alkyl, aryl, aryl alkyl c₁₋₈,Heterociclilo and heterociclil c₁₋₈ alkyl -, where each of r³ᵈ is optionally substituted; as well as their salts, N - oxides, metal complexes,Optically Active isomers or metalloids and complex Geometric isomers, with the condition that the compound of formula (1) is not: 2.2 - dioxide 3 - (3-chloropropyl) - 1 - (quinolin-1 - 3 - yl) - 1H - 4.2.1 - [3 - benzoxatiazina 1033629 42] - 3 - [1 - (- 2.2 - dioxide quinolin-1 - 3 - yl) - 1H - benzoxatiazin 4,2,1 - 3 - yl] - N - [1 - 1033628 metilpropan - Amine and - 19 - 1] 3 -, dihydrochloride [- 2,2 - dioxide 1 - (quinolin-1 - 3 - yl) - 1H - 4.2.Benzoxatiazin - 1 - 3 - yl] - N - [1 - metilpropan Amine 1033625 - 98 - 7].