method for detecting or identifying an infectious or genomic viral polynucleotide sequence in a mammalian cell, tissue or biological fluid, method for detecting or tracking viral presence, viral replication or viral genomic rearrangements in a mammalian cell, method for evaluating efficacy of an antiviral treatment, probe set, kit to perform molecular combing and biological materials.

摘要

A method for easily, rapidly and accurately detecting rearrangements of HPV DNA in a host cell, tissue or biological fluid obtained from a subject or patient using Molecular Combing and/or DNA stretching in combination with specially designed probes for the infectious viral or pathogenic DNA sequence.