methods for detecting an exel 9 deletion mutation in the calreticulin gene exon 9, for diagnosing a hematopoietic disease in a patient, for determining the likelihood of a patient developing a mutation in a jak-stat pathway gene to determine the prognosis of a patient with a myeloproliferative disease, kit, and oligonucleotide probe or primer

摘要

provided herein are methods and compositions for detecting deletion germline mutations in the calr gene. Methods are also provided to determine the prognosis of myeloproliferative diseases and the likelihood of developing somatic mutations in genes involved in the jak-stat pathway.