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Antisenescentes compounds and Uses Thereof

机译:抗衰老化合物及其用途

摘要

This referred to a Peptide comprising the Amino Acid Sequence ltlrkepaseiaqsileaysqngwanrrsggkrp, in which amino acids in this Sequence are residues of D - amino acidA Peptide that has at least 70% identity with the sequence or a Peptide fragment,Which feature of Apoptosis Inducing activity in senescent cells or cells that have a foxo4 expression increased.It also relates to a Pharmaceutical composition containing, being useful in the treatment of age-related disorders, such as atherosclerosis,Chronic inflammatory diseases, cancer, arthritis or Osteoarthritis, Scoliosis, among others
机译:这是指包含氨基酸序列ltlrkepaseiaqsileaysqngwanrrsggkrp的肽,其中该序列中的氨基酸是D-氨基酸的残基与该序列或肽片段具有至少70%同一性的肽,其具有衰老中凋亡诱导活性的特征细胞或具有foxo4表达增加的细胞。它还涉及药物组合物,其包含可用于治疗与年龄有关的疾病,例如动脉粥样硬化,慢性炎症性疾病,癌症,关节炎或骨关节炎,脊柱侧弯等

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