Diagnostic test for detecting the Lynch syndrome, preferably in the Polish population

摘要

the object of the application is a way for detection of genetically conditioned suitability to band lynch, characterized by that,in a sample of genetic material taken from the patient is the presence of constitutional changes within the gene epcam, especially c mutation.858 + 2478 _ * 4507del, with the presence of such changes is genetically conditioned predisposition to band lynch in the patient.in addition, the application also contains mutations in the gene epcam, especially c mutation.858 + 2478 _ * 4507del or polinukleotydy, containing such a mutation.or a polypeptide encoded by the gene containing the mutation allele epcam to detect genetically conditioned predisposition to lynch syndrome.the object of the application is also set to detect genetically conditioned predisposition to lynch's team.