首页> 外国专利> Method for predicting a subject's risk of contracting diabetes mellitus and / or metabolic syndrome or for diagnosing metabolic syndrome in a subject

Method for predicting a subject's risk of contracting diabetes mellitus and / or metabolic syndrome or for diagnosing metabolic syndrome in a subject

机译:预测受试者患糖尿病和/或代谢综合征的风险或诊断受试者代谢综合征的方法

摘要

Method for predicting a subject's risk of contracting diabetes mellitus and / or metabolic syndrome or for diagnosing metabolic syndrome in a subject, in which said subject is non-diabetic, comprising the following stages: - determining the level of proneurotensin 1-117 consisting of SEQ ID No. 5 or peptides comprising proneurotensin 1-117 with an immunoassay or determining the level of proneurotensin 1-117 in a body fluid obtained from said subject, wherein said peptides comprising proneurotensin 1-117 are selected from the group comprising SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 6; and - correlating said level of proneurotensin 1-117 or peptides comprising proneurotensin 1-117 with the risk of said subject of contracting diabetes mellitus and / or metabolic syndrome, in which a high level is predictive of an increased risk of presenting diabetes mellitus and / or metabolic syndrome, or in which an elevated level correlates with the diagnosis of metabolic syndrome in a subject, in which said subject is non-diabetic.
机译:预测受试者患有糖尿病和/或代谢综合征或在受试者中诊断代谢综合征的风险的方法,其中所述受试者为非糖尿病患者,其包括以下阶段:-确定由SEQ组成的神经降压素1-117的水平ID 5或包含免疫原性或测定得自所述受试者的体液中神经降压素1-117的水平的包含神经降压素1-117的肽,其中所述包含神经降压素1-117的肽选自包含SEQ ID No.1的组。 1,SEQ ID No.2,SEQ ID No.6; -将神经降压素1-117或包含神经降压素1-117的肽的所述水平与所述受试者患有糖尿病和/或代谢综合征的风险相关联,其中高水平预示存在糖尿病和/或糖尿病的风险增加。或代谢综合征,或其中升高的水平与受试者的代谢综合征的诊断相关,其中所述受试者是非糖尿病的。

著录项

  • 公开/公告号ES2684512T3

    专利类型

  • 公开/公告日2018-10-03

    原文格式PDF

  • 申请/专利权人 SPHINGOTEC GMBH;

    申请/专利号ES20130708803T

  • 发明设计人 BERGMANN ANDREAS;MELANDER OLLE;

    申请日2013-03-08

  • 分类号G01N33/68;

  • 国家 ES

  • 入库时间 2022-08-21 12:48:22

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