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LACTOBACILLUS JOHNSONII LA1 NCC533 (CNCM I-1225) AND IMMUNE DISORDERS

机译：乳杆菌约翰逊二世LA1 NCC533（CNCM I-1225）和免疫疾病

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摘要

The present invention generally relates to the field of preventing and/ortreating inflammatory and infectious disorders,in particular by boosting the endogenous antimicrobial defences. Oneembodiment of the present invention is the use ofnon-replicating L. johnsonii La1 NCC533 (deposit number CNCM I-1225) for usein the treatment or prevention of disorders relatedto the immune system including infections.

机译：本发明总体上涉及预防和/或预防领域。治疗炎症和感染性疾病，特别是通过增强内源性抗菌素防御能力。一本发明的实施例是使用非复制约翰逊乳杆菌La1 NCC533（保藏号CNCM I-1225）使用在治疗或预防相关疾病免疫系统，包括感染。

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公开/公告号CA2761444C

专利类型
公开/公告日2018-04-24

原文格式PDF
申请/专利权人 NESTEC S.A.;
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申请/专利号CA20102761444
发明设计人 PETIT VALERIE;GARCIA-RODENAS CLARA;JULITA MONIQUE;PRIOULT GUENOLEE;MERCENIER ANNICK;NUTTEN SOPHIE;
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申请日2010-05-07
分类号A61K35/747;A61P31;
国家 CA
入库时间 2022-08-21 12:48:17

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外文文献

1. Scientific Opinion on the substantiation of health claims related to Lactobacillus johnsonii NCC 533 (La1) (CNCM I‐1225) and improving immune defence against pathogenic gastro‐intestinal microorganisms (ID 896), and protection of the skin from UV‐induced damage (ID 900) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 [J] . EFSA Journal . 2011,第6期

2. The effect of Lactobacillus johnsonii Ncc533 (La1) on the balance of Thl/Th2 cells in BALB/c mice [J] . JunliY., WenL., RuopengS., Clinical and investigative medicine: Medecine clinique et experimentale . 2011,第4期

3. Prophylactic effect of oral administration of Lactobacillus johnsonii NCC533 (La1) during the weaning period on atopic dermatitis in NC/NgaTnd mice. [J] . Tanaka A, Fukushima Y, Benyacoub J, European journal of dermatology: EJD . 2008,第2期

4. Lactobacillus rhamnosus TUST006 Enhance the Function of Immunity in BALB/c Mice [C] . Liu Hui-ping, Ma Li, Yan Qing-quan, 5th International Conference on Bioinformatics and Biomedical Engineering . 2011

5. Molecular characterization of IS1223 and localization of the insertion element to strategic positions in the genome of Lactobacillus johnsonii. [D] . Walker, Donald Carey. 1999

6. Cell Surface-Associated Elongation Factor Tu Mediates the Attachment of Lactobacillus johnsonii NCC533 (La1) to Human Intestinal Cells and Mucins [O] . Dominique Granato, Gabriela E. Bergonzelli, Raymond David Pridmore, 2004

7. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to Lactobacillus johnsonii NCC 533 (La1) (CNCM I-1225) and improving immune defence against pathogenic gastro-intestinal microorganisms (ID 896), and protection of the skin from UV-induced damage (ID 900) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 [O] . Tetens Inge 2011