METHOD FOR DETERMINING RISK OF DEVELOPING EXFOLIATION SYNDROME OR EXFOLIATION GLAUCOMA

摘要

A method for assisting the diagnosis of the risk of developing exfoliation syndrome or exfoliation glaucoma in a subject, said method comprising: an allele measurement step of measuring alleles for at least 30 single nucleotide polymorphisms (SNPs) including the 12 core SNPs listed in Table 1 and SNPs selected from the pool SNPs listed in Table 2 (selected pool SNPs), on the basis of SNP allele information in a biological sample collected from the subject; an information acquisition step of acquiring information about the risk of developing exfoliation syndrome or exfoliation glaucoma in the subject on the basis of the results of the measurement of the alleles; and an information provision step of providing information for determining the risk of developing exfoliation syndrome or exfoliation glaucoma in the subject on the basis of the information acquired in the preceding step. According to the method of the present invention, it becomes possible to determine the presence or absence of the risk of developing exfoliation syndrome or exfoliation glaucoma in a subject and predict the degree of the aforementioned risk in the subject, by analyzing SNPs of the present invention occurring in a sample from the subject.