首页> 外国专利> MIR-96 FOR PROTECTING LIVERS, MUSCLES, LUNGS, AND KIDNEYS, FOR REGULATING CONTENT OF TOTAL PROTEIN AND CONTENT OF ALBUMIN IN BLOOD, AND FOR INSULIN RESISTANCE

MIR-96 FOR PROTECTING LIVERS, MUSCLES, LUNGS, AND KIDNEYS, FOR REGULATING CONTENT OF TOTAL PROTEIN AND CONTENT OF ALBUMIN IN BLOOD, AND FOR INSULIN RESISTANCE

机译:MIR-96用于保护肝脏,肌肉,腰部和肾脏,调节血液中总蛋白和白蛋白含量,以及抗胰岛素性

摘要

Provided are an application of miR-96 function inhibition in protecting livers and muscles, in preventing and/or treating kidney diseases and complications thereof and diseases and symptoms related to the decrease of the content of total protein and the content of albumin in blood, and in insulin resistance, an application of miR-96 function enhancement in enhancing lung function, a method for miR-96 function enhancement, and an application of the detection of miR-96 expression level in blood in predicting whether an individual has the risk of suffering liver, kidney and lung diseases. By making a miR-96 inhibitor be in contact with a target cell expressing miR-96, diseases caused by the increase of the amount of miR-96 can be effectively prevented and/or treated; in addition, a miR-96 enhancer can increase lung weight, thereby protecting lung function.
机译:提供了miR-96功能抑制在保护肝脏和肌肉,预防和/或治疗肾脏疾病及其并发症以及与血液中总蛋白质含量和白蛋白含量降低有关的疾病和症状中的应用,以及在胰岛素抵抗中,miR-96功能增强在增强肺功能中的应用,miR-96功能增强的方法,以及检测血液中miR-96表达水平在预测个人是否有患病风险中的应用肝,肾和肺疾病。通过使miR-96抑制剂与表达miR-96的靶细胞接触,可以有效地预防和/或治疗由miR-96量增加引起的疾病;此外,miR-96增强剂可增加肺部重量,从而保护肺功能。

著录项

  • 公开/公告号WO2018121743A1

    专利类型

  • 公开/公告日2018-07-05

    原文格式PDF

  • 申请/专利权人 PENGEKIPHEN BIOTECH LIMITED;

    申请/专利号WO2017CN119889

  • 发明设计人 PENG CHANGGENG;WEN TING;

    申请日2017-12-29

  • 分类号A61K48;A61K31/7088;A61P3/06;A61P1/16;A61P3/04;A61P3/10;

  • 国家 WO

  • 入库时间 2022-08-21 12:43:34

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