首页> 外国专利> Composition for preventing and treating inflammatory and allergic diseases containing complex extract of Raphanus sativus L. Momordicae grosvenori Swingle and Juncus effusus L. var. decipiens Buchen.

Composition for preventing and treating inflammatory and allergic diseases containing complex extract of Raphanus sativus L. Momordicae grosvenori Swingle and Juncus effusus L. var. decipiens Buchen.

机译:用于预防和治疗发炎和变态反应性疾病的组合物,其包含萝卜萝卜(Raphanus sativus L. Momordicae grosvenori Swingle和Juncus effusus L. var)的复合提取物。决定布亨。

摘要

The present invention relates to a composition for preventing and treating inflammatory and allergic diseases containing a complex extract of Raphanus sativus L., Momordicae grosvenori Swingle and Juncus effusus L. var. decipiens Buchen. as an active ingredient. The extract of the present invention has excellent anti-inflammatory, anti-allergic and anti-asthmatic effects such as inhibiting formation of NO, TNF-a and IL-6 cytokine secreted from macrophage after LPS stimulation, inhibits emission of -Hex and formation of LTC4 secreted from mast cells, inhibiting formation of IgE, IL-4, IL-5 and IL-13 in a bronchoalveolar lavage solution of an asthma animal model induced from ovalbumin and inhibiting formation of IL-4, IL-5 and IL-13 in lung, thereby being usefully used for preventing and treating inflammatory and allergic diseases.
机译:本发明涉及一种用于预防和治疗炎性和过敏性疾病的组合物,该组合物包含萝卜(Raphanus sativus L.),罗汉果苦瓜(Momordicae grosvenori Swingle)和juncus effusus L. var的复合提取物。决定布亨。作为有效成分。本发明的提取物具有优异的抗炎,抗过敏和抗哮喘作用,例如抑制LPS刺激后巨噬细胞分泌的NO,TNF-α和IL-6细胞因子的形成,抑制-Hex的释放和β-己内酰胺的形成。 LTC4从肥大细胞分泌,抑制卵清蛋白诱导的哮喘动物模型的支气管肺泡灌洗液中IgE,IL-4,IL-5和IL-13的形成,并抑制IL-4,IL-5和IL-13的形成因此,它可有效地用于预防和治疗炎症和过敏性疾病。

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