NOTCH1 A PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING BREAST CANCER CONPRISING NOTCH1 PHOSPHORYLASE

摘要

The present invention relates to a phospho-Notch1-IC antibody recognizing the Notch intracellular domain (Notch1-IC) threonine 2512 (T2512) phosphorylation and a method for diagnosing cancer using the antibody. The present invention also relates to a composition for preventing or treating breast cancer comprising homeodomain-interacting protein kinase 2 (HIPK2) as an active ingredient, and a method of preventing or treating breast cancer using the same.