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SNP markers for predicting clinical response to anticancer drugs and prognosis in patients with non-small cell lung cancer and uses thereof

机译:用于预测非小细胞肺癌患者对抗癌药物的临床反应和预后的SNP标志物及其用途

摘要

The present invention relates to two SNP markers present in the 3'-UTR of the PD-L1 gene, and a method of providing information for predicting the response and prognosis of anticancer drugs in patients with non-small cell lung cancer. Since the specific genotype of the SNP markers of the present invention is significantly correlated with the response to the paclitaxel-cisplatin chemotherapeutic agent treatment and the survival prognosis of patients with non-small cell lung cancer, the present invention provides a simple and efficient method for determining the reactivity and survival period of non- . / RTI
机译:本发明涉及存在于PD-L1基因的3'-UTR中的两个SNP标记,以及提供用于预测非小细胞肺癌患者中抗癌药物的应答和预后的信息的方法。由于本发明的SNP标志物的特定基因型与对紫杉醇-顺铂化疗药的治疗反应和非小细胞肺癌患者的生存预后显着相关,因此本发明提供了一种简单有效的方法确定非-的反应性和生存期。

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