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Total Synthesis of Cissy Mythin A and Analogs Thereof

机译:西西神话A的全合成及其类似物

摘要

In one aspect, the present invention provides a cyclic mimetic of Formula I: Formula I In the formula (I) The variables are as defined herein. In another aspect, the present invention also provides a process for the preparation of the compounds disclosed herein. In another aspect, the invention also provides pharmaceutical compositions and methods of using the compounds disclosed herein. In addition, antibody drug conjugates of the compounds are also provided.
机译:一方面,本发明提供式I的环状模拟物:式I在式(I)中,变量如本文所定义。在另一方面,本发明还提供了制备本文公开的化合物的方法。在另一方面,本发明还提供了药物组合物和使用本文公开的化合物的方法。另外,还提供了化合物的抗体药物缀合物。

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