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New Biomarker for Diagnosis of Vitiligo Susceptibility and method for predicting assessment using the same

机译:诊断白癜风易感性的新生物标志物和使用该标志物的评估方法

摘要

The present invention relates to a biomarker capable of predicting occurrence of vitiligo and a prediction evaluation method using the same. The present invention has an effect of increasing treatment efficiency of vitiligo by early diagnosis and treatment of vitiligo in a simple and quick manner. Further, the present invention can be usefully used to predict the occurrence of vitiligo in cosmetic components or products. The method comprises the steps of: collecting a skin sample from a patient with suspected vitiligo; separating epidermis from the collected sample; culturing keratinocytes from the separated epidermis; and measuring Nrf2 protein expression level of the cultured keratinocytes and comparing the expression level of Nrf2 protein in the keratinocytes of a control group.
机译:本发明涉及能够预测白癜风的发生的生物标志物以及使用该生物标志物的预测评价方法。本发明具有通过简便快捷地对白癜风的早期诊断和治疗来提高白癜风的治疗效率的效果。此外,本发明可有效地用于预测化妆品成分或产品中白癜风的发生。该方法包括以下步骤:从疑似白癜风患者中收集皮肤样本;从收集的样品中分离表皮;从分离的表皮中培养角质形成细胞;测量培养的角质形成细胞的Nrf2蛋白表达水平,比较对照组角质形成细胞中Nrf2蛋白的表达水平。

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